How to Solve Diseases with Existing Drugs

My blog guests this week are Amy Conn, Bruce Bloom, and Clare Thibodeaux from Cures Within Reach. Disclosure: I am a member of their Advisory Board, and think that testing older drugs for rare diseases is brilliant! The power of repurposing What if the latest treatment for cancer, diabetes or thousands of other unsolved diseases … Continue reading How to Solve Diseases with Existing Drugs

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Oops! Don’t Buy Chocolate Milk for Concussions

No, really. This is a real thing, created by money. Oops, I meant to say, created by researchers and institutions with MAJOR conflicts of interest. Why post it? Well, while this is the most blatant example we've seen in a long time, it happens every day, even to well-meaning researchers. FACT: research is a money game. … Continue reading Oops! Don’t Buy Chocolate Milk for Concussions

Getting Real about Patients & Clinical Trials

I've been asked countless times to write about patients and clinical trials. Guess it's time to share what I've learned, along with other patient advocates, as we work beside researchers in the proverbial trenches. Just so happens that this post coincides with April Fool's Day - hope that's not an omen! Why this series? This is the first in … Continue reading Getting Real about Patients & Clinical Trials

A Clinical Trial Failed Patients

Something horrible happened - a clinical trial failed, causing one unexpected death and seriously injuring 5 people. And instead of dealing with a dysfunctional research system, “experts” are spouting off on their own. The few articles written to date focus on the drug (aka the money), not on what people want to know. My Initial Thoughts ClinicalTrialsArena asked … Continue reading A Clinical Trial Failed Patients

Full-Fledged Flu

'Tis the season, folks. Fancy the opportunity to find flu facts while falling onto the sofa. I fear I may have infected a few as I felt the forceful signs form within. Of course, my bout came from fellow flyers during my fortnight of travel. For those flummoxed by my fanciful alliteration, I have an excuse - I'm under the influence of … Continue reading Full-Fledged Flu

When Clinical Trials Don’t Match Their Data

Clinical trials (research studies in people) can help find better treatment, care and prevention for patients. When done well, they answer important questions posed in the protocol (study plan) before the trial starts. Unfortunately, those answers are often not published. Some also don’t have the right study designs, which means the studies won’t tell us what we truly … Continue reading When Clinical Trials Don’t Match Their Data

Antibiotic Resistance – It’s Complicated!

Big words, yes, but we can still figure this out. I've learned a lot about this topic as a patient advocate on antibacterial drug development committees with the Clinical Trials Transformation Initiative (CTTI) and the Brookings Institution. It's really about the bug in the laboratory (lab), not in humans. That has to change if we want better solutions … Continue reading Antibiotic Resistance – It’s Complicated!